Abstract Introduction: recent studies have suggested the use of neck circumference as a parameter capable of identifying risks of cardiometabolic complications and the accumulation of truncal fat caused by both antiretroviral therapy and the lifestyle of people with the human immunodeficiency virus (HIV). Objective: to investigate the relationship between neck circumference and anthropometric indicators and to assess cardiometabolic risk and truncal obesity through proposed cut-off points. Methods: cross-sectional study including 233 people with HIV. Demographic, socioeconomic, lifestyle and clinical data were collected using a structured questionnaire. The anthropometric evaluation included: weight, height, body mass index (BMI) measurements; waist (WC), neck (NC), arm and arm muscle circumferences; triceps and subscapular skinfolds and their sum. ROC curves were constructed to determine the accuracy of NC in predicting cardiometabolic risk in people living with HIV. Results: the sample was 57.5 % male, with a mean age of 38.4 years (95 % CI: 37.2-39.7 years). NC showed a positive and significant correlation with all anthropometric variables analyzed (p < 0.05), and a higher correlation strength with WC and BMI. The NC cut-off point selected as a predictor of risk of cardiac metabolic complications and truncal obesity in women was ≥ 32.4 cm, considering both WC and BMI. For men, the NC cut-off points were different when considering WC (≥ 39.6 cm) and BMI (≥ 38.1 cm) as a reference. It is worth noting that NC performed well in ROC curve analysis for men, while in women it was a poor performance. Conclusion: NC proved to be a promising indicator in the assessment of nutrition and health of people living with HIV, especially in men.

Resumen Introducción: estudios recientes han sugerido el uso de la circunferencia del cuello como parámetro capaz de identificar los riesgos de complicaciones cardiometabólicas y la acumulación de grasa troncal causados tanto por la terapia antirretroviral como por el estilo de vida de las personas con el virus de la inmunodeficiencia humana (VIH). Objetivo: investigar la relación entre la circunferencia del cuello y los indicadores antropométricos y evaluar el riesgo cardiometabólico y la obesidad troncal a través de los puntos de corte propuestos. Métodos: estudio transversal que incluyó a 233 personas con VIH. Se recogieron datos demográficos, socioeconómicos, de estilo de vida y clínicos mediante un cuestionario estructurado. La evaluación antropométrica incluyó: medidas de peso, altura, índice de masa corporal (IMC); circunferencias de cintura (CC), cuello (CN), brazo (CA) y músculo del brazo (MCB); pliegues cutáneos del tríceps y subescapular y su suma. Se construyeron curvas ROC para determinar la precisión de la CN en la predicción del riesgo cardiometabólico en personas que viven con el VIH. Resultados: el 57,5 % de la muestra eran varones, con una edad media de 38,4 años (IC 95 %: 37,2-39,7 años). La CN mostró una correlación positiva y significativa (p < 0,05) con todas las variables antropométricas analizadas, y una mayor fuerza de correlación con la CC y el IMC. El punto de corte de la CN seleccionado como predictor de riesgo de complicaciones metabólicas cardiacas y obesidad troncular en mujeres fue ≥ 32,4 cm, considerando tanto la CC como el IMC. En el caso de los hombres, los puntos de corte de la CN fueron diferentes al considerar como referencia la CC (≥ 39,6 cm) y el IMC (≥ 38,1 cm). Cabe destacar que la CN obtuvo buenos resultados en el análisis de la curva ROC en el caso de los hombres, mientras que en el de las mujeres fue deficiente. Conclusión: la CN demostró ser un indicador prometedor en la evaluación de la nutrición y la salud de las personas que viven con el VIH, especialmente en los hombres.

Abstract Objective: This research aimed to identify the profile of Cognitive Behavioral Therapy supervisors in this country and to know their training to exercise this professional activity. Method: A nationwide online survey was conducted with 180 Cognitive Behavioral Therapy supervisors, 73.8% of whom were female, with a mean age of 40.3 years (SD = 10.03). Results: Among the main results, the intense academic training, training for psychotherapeutic practice and time of clinical experience (12.6 years, SD = 7.64) and supervised experience (7.4 years, SD = 7.26) stand out. Only 27.8% of the participants indicated having received specific training for supervisors and there was a lack of indications of training resources for remote supervision. Conclusion: This is considered the first research to outline the profile of Cognitive Behavioral Therapy supervisors in Brazil, expanding the vision on this professional activity.

Resumo Objetivo: Esta pesquisa teve por objetivo identificar o perfil de supervisores de Terapia Cognitivo-Comportamental no país e conhecer sua formação para exercer essa atividade profissional. Método: Foi realizado um survey online em âmbito nacional com 180 supervisores de Terapia Cognitivo-Comportamental, sendo 73,8% do sexo feminino, com a média de idade de 40,3 anos (DP = 10,03). Resultados: Entre os principais resultados, ressalta-se a intensa formação acadêmica, treinamento para prática psicoterápica e tempo de experiência clínica (12,6 anos, DP = 7,64) e supervisionada (7,4 anos, DP = 7,26). Apenas 27,8% dos participantes indicaram treinamento específico para supervisor e houve uma lacuna de indicativos de treinamentos de recursos para supervisões remotas. Conclusão: Considera-se essa a primeira pesquisa a traçar o perfil de supervisores de Terapia Cognitivo-Comportamental no Brasil, ampliando o olhar para esta atividade profissional.

NaCMC is a biocompatible polymer that can be crosslinked with citric acid to form a gel matrix. Melaleuca oils have antimicrobial and anti-inflammatory properties with potential for wound healing. The goal of this work was to investigate the characteristics of NaCMC-Melaleuca oils gels. The gels were characterized by FTIR, TGA, mechanical analysis, and in vitro swelling and S. aureus inhibition tests. The oils were characterized using chromatography, presenting high values of (1,8-cineol/terpinen-4-ol), and evaluated for confirmation of their effect against S. aureus. The samples showed physical interactions between NaCMC, citric acid and the Melaleuca oils. Erosion in saline solution was higher in the gels with oils, attributable to interference with crosslinking. The membranes presented high contribution of relaxation mechanism and low contribution of Fickian diffusion regarding the swelling ability. The presence of the oils increased thermal stability and diminished gel fraction and mechanical properties, indicating that the oils interact with the matrix anchoring the chains. Although melaleuca oils themselves were active against S. aureus and CA was responsible for the NaCMC hydrogels activity, the incorporation of melaleuca oils in NaCMC gels was not reported previously. This report indicates that NaCMC hydrogel may be a proper matrix for essential oils incorporation.

These two men were former natural philosophy students from the University of Coimbra. Barbacena finished in 1775 and obtained a doctorate in 1776, whereas Maciel graduated in 1785 and then did scientific and industrial work in Portugal and England. The Viscount was a founder member of the Lisbon Academy of Sciences in 1779, and its secretary for 9 years. Both came to Brazil in 1788, when the Viscount was named Governor of Minas Gerais. Insofar as gold production was falling drastically, the Governor-to-be saw in Maciel the right person to start a comprehensive survey of the mineral potential of his domain. Soon after their arrival their lives parted. Without leaving his scientific pursuits, Maciel became embroiled in the planned uprising known as Inconfidência Mineira and was arrested in late 1789. His promising scientific career was aborted at the age of 29 and he was sentenced to exile in Africa. His despondency contributed to an early death at 43. The Viscount’s fate is also gloomy, for in Brazil he is hardly remembered today for any devotion to science, but mainly as the harsh persecutor of patriots.